vicissitude

(feminine) variation (change that occurs in things that happen)
(feminine) chance, eventuality
(feminine) adversity, reversal (change of circumstances or conditions, usually unfavorable)
(feminine) setback

μεταστροφή

περιπέτεια

μετάπτωση

μεταλλαγή

vicissitudo

onbestendigheid

istikrarsızlık

Learned borrowing from Latin vicissitūdō.

Practice speaking and memorizing "vicissitude" and many other words and sentences in Portuguese.